Linkage disequilibrium and diversity for three genomic regions in Azoreans and mainland Portuguese

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Linkage disequilibrium and diversity for three genomic regions in Azoreans and mainland Portuguese

Studies on linkage disequilibrium (LD) across the genome and populations have been used in recent years with the main objective of improving gene mapping of complex traits. Here, we characterize the patterns of genetic diversity of HLA loci and evaluate LD (D') extent in three genomic regions: Xq13.3, NRY and HLA. In addition, we examine the distribution of DXS1225-DXS8082 haplotype diversity i...

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ژورنال

عنوان ژورنال: Genetics and Molecular Biology

سال: 2009

ISSN: 1415-4757

DOI: 10.1590/s1415-47572009000200003